When you load the menu option, the values you see displayed will be the values currently in use by your game. Vanilla values are 3.3 and 2.0. If the menu is displaying different values, then you have a mod installed which is already adjusting these two settings. If you choose to select a new setting, Trade & Barter will override the settings from the other mod. If at any time you wish to revert the settings back to those made by another mod, simply deselect this setting and reload your game. You will need to reload your game before the changes from Trade & Barter are fully canceled out.
Trade in Skyrim is oversimplified and uninteresting. A particular type of merchant always has the same amount of gold and offers you the exact same prices as the same type of merchant in another part of the country. Merchants in small towns differ very little from those in the larger cities, and the only factors that affect price are your speech skill and any barter enchantments you might have.